Moringa oleifera and ovarian cancer



Ovarian cancer is caused by the proliferation of organ cells, most often by epithelial cells and not by those that produce ova.

A hormonal etiological origin has been demonstrated in relation to the menopause of ovaric carcinoma; in fact the epithelium of the ovary is hormonally active and the follicle stimulating hormone (FSHR) receptors have been recognized as endogenous carcinogens for carcinoma. It affects, mainly, women between 50 and 65 years old but can occur even at a young age.

The greatest difficulty in managing this tumor is given by the difficult identification as it starts to show symptoms only when it is already at an advanced stage.

This motivates the great importance of prevention controls.

Moringa oleifera, used for centuries as a traditional medicine, is widely studied to discover and prove its effectiveness in various diseases. In fact, every part that makes up the plant has different pharmacological characteristics.

They are recognized to it: a very high antioxidant, antibacterial, anti-inflammatory, antifungal power. Moreover, in studies carried out and existing in the bibliography its effectiveness on the treatment of diabetes and hypertension has been demonstrated.

Which substances attribute to the moringa "curative" effects?

Moringa oleifera contains a unique combination of isothiocyanates and glucosinolates; antitumor compounds that inhibit certain stages of carcinogenesis, important in the treatment of female reproductive disorders. The effectiveness of the Moringa plant in the treatment of ovarian cancer is evidenced by recent studies showing that benzyl isothiocyanate and phenyl isothiocyanate induce apoptosis, which is a form of cell death programmed in ovarian tumor cells in vitro.

Isothiocyanates have already been identified for their antitumor activity in breast, skin, esophagus and lung cancers.

Furthermore, the Moringa has a double effect because it also has a hormonal activity by implementing a hormone-related receptor control mechanism that is effective in estrogen-dependent tumors as it is able to rebalance the production of the estrogens involved.

To combat estrogen-dependent tumors, drugs are used that reduce the synthesis of estrogen and block its biological action.

Studies involving Moringa oleifera could lead to products that can assist pharmacological treatment as, in addition to the widely described characteristics, a potential chemo-preventive effect against carcinogens passing the body's hepatic pathway has been demonstrated.

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